One hundred eighty infants with oxygen therapy who were under 2,500gm birth weight or under 37 weeks of gestational age, were examined between January 1990 and November 1992. We performed clnical analysis and results were as follows.
1) Fifty six infants (31.1%) were diagnosed as retinopathy of prematurity.
2) The first examination was performed at 2.5 weeks of life on average, and the retinopathy of prematurity was diagnosed at 3.8 weeks on average.
3) The incidence of retinopathy of prematurity was highly associated with low birth weight (≤1,890 gm), low gestational age ( ≤33.1 weeks), and high oxygen concentration with long duration (FiO2≥0.4 over 1 week)(P<0.005).
4) Other associated risk factors were idiopathic respiratory distress syndrome, anemia, neonatal hypoxia and sepsis.
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